منابع مشابه
renal cell protection of erythropoietin beyond correcting the anemia in chronic kidney disease patients
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متن کاملProtection against ischemia/reperfusion‑induced renal injury by co‑treatment with erythropoietin and sodium selenite.
Ischemia/reperfusion injury (IRI) has lzong been an area of concern and focus of investigations. Erythropoietin (EPO) exhibits multiple protective effects, and selenium is an antioxidant trace element in the body, however, there have been no reports concerning the effects of EPO combined with sodium selenite on IRI. In the present study, a mouse model of renal IRI (RIRI) was pre‑treated with EP...
متن کاملCombination Antioxidant Effect of Erythropoietin and Melatonin on Renal Ischemia-Reperfusion Injury in Rats
Objective(s): Renal ischemia reperfusion (IR) contributes to the development of acute renal failure (ARF). Oxygen free radicals are considered to be principal components involved in the pathophysiological tissue alterations observed during renal IR. The purpose of this study was to investigate the effect of co-administration of melatonin (MEL) and erythropoietin (EPO), potent antioxidant and ...
متن کاملErythropoietin production in renal tumors.
A review of the pertinent literature on the relation of erythropoietin production to the presence of renal neoplasm suggests that erythropoietin may be produced either directly by the tumor or indirectly by its physical effect on the adjoining normal renal tissue. The most commonly found tumors which are associated with elevated levels of serum and urinary erythropoietin are the hypernephromas....
متن کاملRenal Cell Protection of Erythropoietin beyond Correcting The Anemia in Chronic Kidney Disease Patients
Currently many patients with chronic renal failure have profited from the use of erythropoietin to correct anemia (1,2). In chronic kidney disease, anemia is believed to be a surrogate index for tissue hypoxia that continues preexisting renal tissue injury (1-3). Erythropoietin is an essential glycoprotein that accelerates red blood cell maturation from erythroid progenitors and facilitates ery...
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ژورنال
عنوان ژورنال: DARU Journal of Pharmaceutical Sciences
سال: 2013
ISSN: 2008-2231
DOI: 10.1186/2008-2231-21-78